The Federal Office for Safety in Health Care was informed by the Danish authority that it had been informed by the Danish tissue bank Cryos International (DK257551) of a termination of a pregnancy at 16 weeks' gestation due to abnormalities of the fetus in all four limbs. The report describes the clinical picture arthrogryposis multiplex congenita (AMC).

The Federal Office for Public Health Safety has been informed by the Romanian authorities that, in addition to the already known regions, further confirmed human WNV infections (meningitis/encephalitis) have occurred in the regions of Giurgiu, Satu Mare and Iasi.

The Federal Office for Public Health Safety has been informed by the Italian authority that 52 human cases of WNV infection have been confirmed in the regions of Veneto and Emilia-Romagna. Entomological and veterinary surveillance confirmed the circulation of WNV in the affected regions and additionally in the regions of Lombardy and Piedmont.

The Federal Office for Public Health Safety has been informed by the Romanian authority that, in addition to the already known regions, further confirmed human WNV infections (meningitis/encephalitis) have occurred in the regions of Galati, Teleorman and Vrancea.

The Federal Office for Public Health Safety has been informed by the French authority that the first human WNV infection has been confirmed in Nice.

The Federal Office for Public Health Safety has been informed by the Romanian authorities that, in addition to the already known regions, further confirmed human WNV infections (meningitis/encephalitis) have occurred in the regions of Bacau, Bucuresti, Ilfov and Botosani.

The European Medicines Agency (EMA) is currently conducting an investigation into the potential health effects on patients who have taken valsartan medicines containing the impurity NDMA. NDMA is an impurity found in the active ingredient valsartan,…

Preliminary risk assessment of NDMA for patients

New versions of the electronic Application Forms (eAF v. 1.23) and related documents are available via the EMA-website ( http://esubmission.ema.europa.eu/eaf/ ). Specific information from the BASG are published on…

The Federal Office for Public Health Safety has been informed by the Romanian authority that, in addition to the regions already announced, three confirmed human WNV (meningitis/encephalitis) infections have occurred in the regions of Dolj and Lasi.