The 2016/2017 yellow fever outbreak in Brazil was declared over in September 2017. The upsurge of human cases since December 2017 and non-human primate epizootics since September 2017 indicates a resurgence of the circulation of yellow fever virus in Brazil, and more particularly in São Paulo State.

The Federal Office for Safety in Health Care was informed by the Danish authority that it was informed by the Danish tissue bank Cryos International ApS (DK257551) about the disease of a child conceived with the semen of sperm donor 5971.

The Federal Office for Safety in Health Care was informed by the Danish authority that it was informed by the Danish tissue bank Nordic Cryobank ApS - NCB - (European Sperm Bank) about a microduplication in the PAR1 regionXp22.33/Yp11.32 in sperm donor 8040/ADLER. The duplication was verified by multiplex ligation-dependent probe amplification(MLPA; probemix P018-G1 SHOX, MRC-Holland). The duplication does not involve the SHOX gene but is located downstream in the regulatory region.

The Federal Office for Public Health Safety has been informed by the French authority that the first human WNV infection has been confirmed in Nice. Therefore, the French authority extends the seasonal WNV surveillance until November 15, 2017.

Italy is currently experiencing four clusters of autochthonous chikungunya cases in the cities of Anzio, Latina and Rome in the Lazio region, and the city of Guardavalle Marina in the Calabria region. Autochthonous transmission of mosquito-borne infections is not unexpected in areas where Aedes albopictus mosquitoes are established and at a time when environmental conditions are favouring mosquito abundance and activity.

The Federal Office for Public Health Safety has been informed by the Romanian authorities that two new human WNV (meningitis/meningoencephalitits) infections have been confirmed in the capital city of Bucharest.

The Federal Office for Public Health Safety has been informed by the Italian authority that four confirmed cases of malaria have been recorded in non-EU citizens in Italy (Apulia Region: Ginosa, Taranto Province).

The Federal Office for Public Health Safety has been informed by the Italian authority that two more confirmed autochthonous chikungunya cases have been recorded. The reports themselves come from Rome - Lazio Region and Reggio Emilia - Emilia Romagna Region.

186 Total notified cases

The Federal Office for Public Health Safety has been informed by the Romanian authority that, in addition to the regions already announced, a confirmed human WNV infection (meningitis/encephalitis) has occurred in the Calarasi region.