The Federal Office for Safety in Health Care was informed by the Danish authority that it was informed by the Danish tissue bank "European Sperm Bank (formerly Nordic Cryobank)" (DK267572) about the disease of a sperm donor. Investigations showed that sperm donor 8311 / Bonne is heterozygous for mutation c.1062 + 5G> A in the FAH gene and thus a carrier of tyrosinemia type 1 (hepatorenal tyrosinemia, HT-1).

The Federal Office for Safety in Health Care has been notified by the Danish authority that it has been informed by the Danish tissue bank Cryos International ApS (DK257551) about the disease of a 2-year-old child conceived with semen from donor 8151. The report of the disease describes a child with autism spectrum disorder (ASD).

The Federal Office for Safety in Health Care has been notified by the Danish authority that it has been informed by the Danish tissue bank Cryos International ApS (DK257551) of the disease of a child conceived with semen from donor 1291-KELD.The report of the disease described oculocutaneous albinism type 1 (OCA1) in the child, due to mutations in the TRY gene, which encodes the protein tyrinase.

The Federal Office for Public Health Safety has been informed by the French authority that a sharp increase in dengue virus cases has been recorded on Reunion Island since January 2018.

The Federal Office for Safety in Health Care has been informed by the Danish authority that it has been informed by the Danish tissue bank Cryos International ApS (DK257551) about the diseases of children conceived with the semen of the following sperm donors

The Federal Office for Safety in Health Care has been informed by the Danish authority that it has been informed by the Danish tissue bank Cryos International ApS (DK257551) about the disease of a child conceived with the semen of sperm donor 6932. The report of the disease describes a child with developmental delay. Genetic testing by aCGH (array - comparative genomic hybridization) revealed a 4.6Mb deletion on chromosome 3p22.

The Federal Office for Safety in Health Care was informed by the Danish authority that it was informed by the Danish tissue bank Cryos International ApS (DK257551) about the disease of a child conceived with the semen of sperm donor 3614. The report of the condition described a 6-year-old child diagnosed with Asperger syndrome with signs of ADHD (attention deficit hyperactivity disorder).

The 2016/2017 yellow fever outbreak in Brazil was declared over in September 2017. The upsurge of human cases since December 2017 and non-human primate epizootics since September 2017 indicates a resurgence of the circulation of yellow fever virus in Brazil, and more particularly in São Paulo State.

The Federal Office for Safety in Health Care was informed by the Danish authority that it was informed by the Danish tissue bank Cryos International ApS (DK257551) about the disease of a child conceived with the semen of sperm donor 5971.

The Federal Office for Safety in Health Care was informed by the Danish authority that it was informed by the Danish tissue bank Nordic Cryobank ApS - NCB - (European Sperm Bank) about a microduplication in the PAR1 regionXp22.33/Yp11.32 in sperm donor 8040/ADLER. The duplication was verified by multiplex ligation-dependent probe amplification(MLPA; probemix P018-G1 SHOX, MRC-Holland). The duplication does not involve the SHOX gene but is located downstream in the regulatory region.